According to a report, Sony is going ahead with another Spider-Man spinoff. Much like this year’s Venom, the film is a Spidey-themed film but is not apart of the MCU.
Silk, Cindy Moon was bitten by the same spider that gave Peter Parker his powers. Instead of using her abilities she was kept locked away in a bunker until the recent Spider-verse event. She also had her own short-run series.
Cindy Moon has appeared in the MCU as well, played by Tiffany Espensen. Cindy has appeared in Spider-Man Homecoming and had a cameo in Avengers Infinity Wars.